The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry/C. Someswara Rao. Reprint. New Delhi, Asian Books Private Limited, 2006, xvi, 1311 p., $120. ISBN 81-86299-77-7.

    Contents: Preface. 1. The nature of process development. 2. Survey of some organic reactions in relation to process development. 3. Chiral technology. 4. Strategies for simplification of organic reactions and processes. 5. Reagent modification and rate and order of addition of reagents. 6. Additives for reagents-fine tuning of organic reactions. 7. Choosing a reagent. 8. By-products from side reactions. 9. Solvents and solvents effects. 10. Phase transfer catalysis. 11. Work-up, purity, and purification. 12. Safety assessment of chemical process technology. References. Index.

    "In fine chemical and pharmaceutical industry not only individual organic reactions but also the overall processes have to be optimized on an increasing scale with respect to cost-effectiveness, safety and atom economy. This book aims to elaborate on the various chemical strategies available for this purpose. It is meant to be useful to development chemists in R&D divisions of chemical industry, to process research chemists and to basic research chemists, with a passion to improve atom economy in organic reactions. The present structuring of the topic is aimed at stimulating their interest in critical areas of process development." (jacket)

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