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Drug Disposition and Pharmacokinetics With a Consideration of Pharmacological and Clinical Relationships

Stephen H. Curry, PharmaMed Press, 2008, pbk, Third Edition, xviii, 330 p, 102 figs, ISBN : 81-88449-58-X, $28.00 (Includes free airmail shipping)
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Drug Disposition and Pharmacokinetics With a Consideration of Pharmacological and Clinical Relationships/Stephen H. Curry

Contents: Preface. Preface to third edition. Introduction. 1. Chemical introduction: drug sources, drug classification and chemical properties of drugs. 2. Disposition and fate. 3. Binding to plasma proteins. 4. Drug concentrations in blood and blood fractions. 5. Factors affecting plasma concentrations. 6. Bioavailability. 7. Developmental pharmacology and age-related drug phenomena. 8. Pharmacogenetics. 9. Effects of disease on quantitative pharmacology. 10. Elementary pharmacokinetics. 11. Quantitative evaluation of urinary excretion. 12. Drug interactions. 13. Quantitative pharmacological relationships. 14. Drug monitoring in therapeutics. 15. Drug toxicity. Appendices: i. Drug analysis. ii. Multiple dosing. iii. Antibiotic dosage regimens which allow for pharmacokinetic variations. iv. Further general reading in pharmacology.

"The substantial changes in this book reflect the many significant advances that have been made since publication of the second edition. It therefore provides a greater understanding of the specific biological factors affecting pharmacokinetic processes of drug toxicity, and the practical uses of pharmacokinetic knowledge. The book remains a highly readable and informative account of the subject which greatly help students and postgraduates of pharmacy and pharmacology to develop a rational approach to the investigation and application of drugs.

Salient features:

Emphasis is given to recent studies on age, genetics and disease.
Rearranged the book with new material and the size has grown accordingly."

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