Subjects

Basic Pharmacokinetics, (With CD)

Mohsen A. Hedaya, Taylor and Francis Group, 2010, pbk, Reprint, xxvi, 300 p, tables, figs, ISBN : 1420046713, $33.00 (Includes free airmail shipping)

Basic Pharmacokinetics, (With CD)/Mohsen A. Hedaya

Contents: 1. Introduction to biopharmaceutics and pharmacokinetics. 2. Drug pharmacokinetics following single intravenous administration. 3. Drug absorption following oral administration: biopharmaceutical considerations. 4. Drug pharmacokinetics following single oral drug administration: rate of drug absorption. 5. Drug pharmacokinetics following single oral drug administration: extent of drug absorption. 6. Steady-state principle and drug pharmacokinetics during constant-rate intravenous infusion. 7. Steady state during multiple drug administrations. 8. Renal drug elimination. 9. Metabolite pharmacokinetics. 10. Disease state and drug pharmacokinetics. 11. Nonlinear pharmacokinetics. 12. Multicompartment pharmacokinetic models. 13. Drug pharmacokinetics following administration by intermittent intravenous infusion. 14. Noncompartmental approach to pharmacokinetic data analysis. 15. Physiological approach to hepatic clearance. 16. Pharmacokinetic-pharmacodynamic relationship. 17. Therapeutic drug monitoring. 18. Solutions to practice problems. Index.

"Pharmacokinetics has become an essential component of all the processes involved in drug development discovery and preclinical evaluation, as well as the clinical use of drugs. While this has led to the development of many highly complex techniques, basic pharmacokinetic concepts remain the backbone of all these new developments.

Basic Pharmacokinetics consists of two parts: textual printed materials and highly interactive computer-based presentations. Together, they provide a useful combination for learners to grasp and understand basic principles. The computer-based information is presented in a self-instructional format, which introduces the concepts, utilizing highly interactive graphical presentations and simulations.

Offering a self-instructional format, Basic Pharmacokinetics....

  • Introduces concepts in a way that does not require an intensive mathematical background.
  • Covers the pharmacokinetic behavior of drugs after single and multiple administration by intravenous, oral and intravenous infusion.
  • Addresses the pharmacokinetic behavior of drugs, which follow single and multiple compartment models and follow linear and nonlinear pharmacokinetics.
  • Continues to serve as a useful reference for more advanced researchers.

Uniquely and carefully designed, the learning modules in the CD closely support and complement the text, providing the learner with an opportunity to assess his or her understanding of the principles presented."

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