Drug Formulations Manual

Contents: 1. Tablets. 2. Injectables. 3. Liquid orals. 4. Capsules and dry syrups. 5. Eye and ear preparations. 6. Topical preparations. Therapeutic index. Active ingredients index.

Pharmaceutical formulation involves development of a bioavailable, stable and optimal dosage form for a specific administration route and successful formulation development takes more than a great idea. It takes technology know how and manufacturing experience to find the best route for your product. It also takes regulatory expertise a commitment from a team of dedicated people and cGMP assets to meet your needs from development through commercial launch. The goal of this book is to assist the reader in identifying the best form of delivery and the most viable manufacturing process for their product. Factors playing a role in devel9opment of a dosage form manufacturing process include manufacturability, consistency of products quality, batch size optimization, yield improvement, SKU reduction and cost optimization. Over five decades of manufacturing experience of each of the authors, ensures that this book can shed new light on how to get your products to market quickly, efficiently and in a cost effective manner. All formulations are validated and based on actual production batches undertaken in various manufacturing facilities. Information on each product is covered under the following heads: Labeled formula, batch size, practical yield, ingredients and batch quantities, manufacturing specifications and manufacturing processes.

There are over four hundred products in this book covering major categories of pharmaceutical formulations: solid dosage formulations (capsules, tablets for immediate release or extended release). Non-sterile liquid formulations for oral administration (syrups, suspensions). Sterile liquid dosage formulations (Opthalmic, oral, nasal). Injectables drugs (Intravenous and intramuscular, subcutaneous injectables). Topical formulations (Creams, gels).