Essential Genetics : A Genomics Perspectives
Contents: Preface. 1. DNA : the genetic code. 2. Mendelian genetics. 3. The chromosomal basis of heredity. 4. Genetic linkage and genetic maps. 5. Variation in chromosome number and structure. 6. The chemical structure and replication of DNA. 7. Mutation and DNA repair. 8. Gene expression. 9. The genetic control of development and regulation of gene activity. Bibliography. Index.
During the process of DNA replication, errors occasionally occur in the polymerization of the second strand. These errors, called mutations, can have an impact on the phenotype of an organism, especially if they occur within the protein coding sequence of a gene. Error rates are usually very low-1 error in every 10-100 million bases-due to the proofreading ability of DNA polymerases. (jacket)
During the process of DNA replication, errors occasionally occur in the polymerization of the second strand. These errors, called mutations, can have an impact on the phenotype of an organism, especially if they occur within the protein coding sequence of a gene. Error rates are usually very low-1 error in every 10-100 million bases-due to the proofreading ability of DNA polymerases. (jacket)
