Pharmaceutical Organic Chemistry

Contents: Preface. 1. Structure and properties of organic compounds. 2. Stereochemistry. 3. Structure, nomenclature and reactions of alkanes. 4. Structure, nomenclature and reactions of alkenes. 5. Structure, nomenclature and reactions of alkynes. 6. Nucleophilic aromatic substitution. 7. a, b-Unsaturated Carbonyl compounds. 8. Conservation of orbital symmetry and rules. 9. Electronic, cycloaddition and sigmatropic reactions. 10. Neighbouring group participation. 11. Catalysis by transition metal complexes. 12. Stereoselective and stereospecific reactions. 13. Organic reagents in drug synthesis. 14. Heterocyclic compounds. 15. Chemistry of lipids. 16. Chemistry of carbohydrates. 17. Chemistry of proteins and nucleic acids. Bibliography. Index.

"This book is the series of pharmacology concentrates its focus on pharmaceutical organic chemistry, which primarily deals in developing carbon compounds for drug development and use. It studies the general concepts of organic chemistry which apply to small, simple carbon compounds to more complex molecules such as carbohydrates, fats and proteins, addressing the issues of their requirements in drug research and development.

The book takes into consideration the exploration of the techniques, principles and practices which underlie organic chemistry in pharmaceutical companies, and the development that is shaping what they represent for the future. In addition, it also looks into current trends and advancements in the field, with an incisive analysis of what implications they carry. The illustrations and diagrams further foster a better understanding of the subject.

The erudition and insight of the book serve well for pharmacology students." (jacket)